Bariatric Surgery as an Efficient Treatment for Non-Alcoholic Fatty Liver Disease in a Prospective Study with 1-Year Follow-up : BariScan Study

Autor: Loay Bokhary, Janina Sollors, Adrian T. Billeter, Felix Nickel, Christian Tapking, Laura Benner, Moritz von Frankenberg, Lars Fischer, Sebastian Mueller, Hannes Kenngott, Mathias Schmid, Beat P. Müller-Stich
Rok vydání: 2017
Předmět:
Adult
Liver Cirrhosis
Male
medicine.medical_specialty
Sleeve gastrectomy
Endocrinology
Diabetes and Metabolism
medicine.medical_treatment
Gastric Bypass
Bariatric Surgery
030209 endocrinology & metabolism
Comorbidity
Body Mass Index
03 medical and health sciences
Liver disease
0302 clinical medicine
Weight loss
Gastrectomy
Non-alcoholic Fatty Liver Disease
Weight Loss
medicine
Humans
Postoperative Period
Prospective Studies
Prospective cohort study
Retrospective Studies
Nutrition and Dietetics
business.industry
Fatty liver
nutritional and metabolic diseases
Middle Aged
medicine.disease
Obesity
digestive system diseases
Surgery
Obesity
Morbid
Treatment Outcome
Research Design
Elasticity Imaging Techniques
030211 gastroenterology & hepatology
Female
Laparoscopy
medicine.symptom
Transient elastography
business
Body mass index
Follow-Up Studies
Zdroj: Obesity surgery. 28(5)
ISSN: 1708-0428
Popis: Bariatric surgery gains attention as a potential treatment for non-alcoholic fatty liver disease (NAFLD). The present study aimed to evaluate improvement of NAFLD after the two most common bariatric procedures with validated non-invasive instruments. N = 100 patients scheduled for laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RYGB) were included. NAFLD was evaluated preoperatively and postoperatively with liver stiffness measurement by transient elastography and laboratory-based fibrosis scores. Clinical data included body mass index (BMI), total weight loss (%TWL), excess weight loss (%EWL), age, gender, comorbidities, and the Edmonton obesity staging system (EOSS). There were significant improvements of BMI, %TWL, %EWL, and EOSS after bariatric surgery. Liver stiffness was significantly improved from pre- to postoperative (12.9 ± 10.4 vs. 7.1 ± 3.7 kPa, p
Databáze: OpenAIRE
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