Retrospective Study of Nephrotoxicity Rate among Adult Patients Receiving Colistin Compared to β-lactam Antibiotics

Autor: M A Raja, Vidyalakshmi Devarajan, Ramesh Nimmagadda, Balasubramaniam Ramakrishnan, Abdul Ghafur, T. V. Raja, Jose Easow, S G Raman, Sankar Sreenivas, Dedeepiya Devaprasad, Nitin Bansal
Rok vydání: 2019
Předmět:
Zdroj: Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
ISSN: 1998-359X
0972-5229
Popis: Purpose Patients receiving colistin for carbapenem-resistant gram-negative bacteria (CR-GNB) infections generally have multiple risk factors for nephrotoxicity, so it might be possible that colistin may be erroneously blamed for the nephrotoxicity. Materials and methods We retrospectively analyzed case records of patients who received colistin and those who received antibiotics other than colistin [carbapenem or β-lactam–β-lactamases inhibitors (βL–βLI)] for gram-negative bacteremia. Those patients with preexisting renal failure and those who received antibiotics for
Databáze: OpenAIRE