Retrospective Study of Nephrotoxicity Rate among Adult Patients Receiving Colistin Compared to β-lactam Antibiotics
Autor: | M A Raja, Vidyalakshmi Devarajan, Ramesh Nimmagadda, Balasubramaniam Ramakrishnan, Abdul Ghafur, T. V. Raja, Jose Easow, S G Raman, Sankar Sreenivas, Dedeepiya Devaprasad, Nitin Bansal |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
Carbapenem Carbapenem resistance medicine.drug_class Antibiotics Renal function Neutropenia Colistin nephrotoxicity injury to the kidney Critical Care and Intensive Care Medicine Nephrotoxicity 03 medical and health sciences 0302 clinical medicine Internal medicine Risk of renal dysfunction polycyclic compounds medicine business.industry 030208 emergency & critical care medicine loss of kidney function biochemical phenomena metabolism and nutrition bacterial infections and mycoses medicine.disease failure of kidney function 030228 respiratory system end-stage kidney disease score Bacteremia Colistin business Research Article Kidney disease medicine.drug |
Zdroj: | Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine |
ISSN: | 1998-359X 0972-5229 |
Popis: | Purpose Patients receiving colistin for carbapenem-resistant gram-negative bacteria (CR-GNB) infections generally have multiple risk factors for nephrotoxicity, so it might be possible that colistin may be erroneously blamed for the nephrotoxicity. Materials and methods We retrospectively analyzed case records of patients who received colistin and those who received antibiotics other than colistin [carbapenem or β-lactam–β-lactamases inhibitors (βL–βLI)] for gram-negative bacteremia. Those patients with preexisting renal failure and those who received antibiotics for |
Databáze: | OpenAIRE |
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