Estimation of the lower limit of quantitation, a method detection performance parameter for biomedical assays, from calibration curves
Autor: | N. Kucharczyk |
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Rok vydání: | 1993 |
Předmět: |
Detection limit
Chromatography Calibration curve Calibration (statistics) Chemistry Myocardium Guinea Pigs General Chemistry Reference Standards Models Biological Lower limit Rats Dogs Spectrometry Fluorescence Pharmaceutical Preparations Animals Humans Detection performance Spectrophotometry Ultraviolet Lung Chromatography High Pressure Liquid |
Zdroj: | Journal of Chromatography B: Biomedical Sciences and Applications. 612:71-76 |
ISSN: | 0378-4347 |
DOI: | 10.1016/0378-4347(93)80369-f |
Popis: | A model for the lower limit of quantitation for biomedical chromatographic assays is proposed. It is based on the IUPAC definition for the limit of detection and can be estimated from assay calibration data. It has been applied to ten different sets of calibration data from various assays of drugs in biological matrices. |
Databáze: | OpenAIRE |
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