Causes and predictors of mortality among Ghanaians hospitalised with endocrine disorders
| Autor: | Eunice Oparebea Ansah, Nana Ama Barnes, Osei Sarfo-Kantanka, Ishmael Kyei |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Longitudinal study medicine.medical_specialty Pediatrics Health (social science) 030209 endocrinology & metabolism endocrine admissions Disease outcomes Endocrine System Diseases Ghana Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Risk Factors Cause of Death West Africa medicine Endocrine system Humans 030212 general & internal medicine Hospital Mortality Longitudinal Studies Survival analysis Aged Proportional Hazards Models Retrospective Studies Inpatient care business.industry Mortality rate Public health Hazard ratio Public Health Environmental and Occupational Health General Medicine Original Articles Middle Aged Hospitalization Female business |
| Zdroj: | International Health |
| ISSN: | 1876-3405 1876-3413 |
| Popis: | BackgroundEndocrine disorders have been noted to be on the increase in the developing world, but little is known about their outcomes on the African continent.MethodsWe conducted a retrospective longitudinal study to evaluate the demographic characteristics and determinants of endocrine-related mortality among adult patients over 9 y in a leading tertiary hospital in Ghana. We determined the predictors of inpatient mortality using Kaplan–Meier survival curves and Cox proportional hazard regression analysis.ResultsOverall, 6265 patients (9.7% of all medical admissions) were admitted with various endocrine disorders during the period. The most common endocrine cause of hospitalisation was diabetes mellitus (86.0%), followed in order of decreasing frequency by thyroid disorders (7.7%) and miscellaneous disorders (1.4%). The overall crude mortality rate of endocrine admissions was 16.7%. Death was predicted by increasing age with an adjusted hazard ratio of 1.25 (95% confidence interval 1.15 to 1.65) for every 10-y increase in age.ConclusionsAlmost one in six adults admitted with an endocrine disorder to a tertiary care centre in Ghana died in hospital, and many of the deaths were due to non-communicable disease complications. Enhanced public health disease prevention strategies and endocrine inpatient care processes are warranted. |
| Databáze: | OpenAIRE |
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