Is CDAI comparable to DAS 28 and SDAI regarding inter-observer agreement and correlation to MHAQ in Egyptian RA patients?
| Autor: | Sherif M. Gamal, N Y Elsaid, S Saad, Khaled T. El-Hadidi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
rheumatoid arthritis
Male lcsh:Internal medicine medicine.medical_specialty Inter observer agreement lcsh:Medicine Positive correlation Severity of Illness Index Statistics Nonparametric Correlation Arthritis Rheumatoid 03 medical and health sciences 0302 clinical medicine Cohen's kappa Rheumatology Internal medicine Medicine Humans 030212 general & internal medicine lcsh:RC31-1245 030203 arthritis & rheumatology Observer Variation DAS 28 MHAQ Chi-Square Distribution CDAI business.industry lcsh:R Reproducibility of Results Simplified disease activity index Middle Aged Clinical disease medicine.disease humanities Rheumatoid arthritis Cohort interobserver agreement Egypt Female SDAI business |
| Zdroj: | Reumatismo, Vol 71, Iss 4 (2020) |
| ISSN: | 0048-7449 |
| Popis: | Choosing between the different disease activity indices used for rheumatoid arthritis RA evaluation in clinical practice and research is often difficult. The aim of the current study was to compare clinical disease activity index (CDAI) to simplified disease activity index (SDAI), and disease activity score 28 (DAS28) regarding inter-observer reliability and correlation to the modified health assessment questionnaire (MHAQ) in a cohort of Egyptian RA patients. This study included one hundred RA patients. Every patient had an independent clinical evaluation made by two rheumatologists (professor and candidate) to evaluate disease activity using DAS28 with its 4 types, CDAI and SDAI. We used Cohen’s weighted kappa coefficient to measure the inter-observer agreement between the professor and candidate in different disease activity measures. Correlation between MHAQ and disease activity measures was made with Spearman’s rho test. Inter-observer agreement in CDAI and DAS28 values was almost perfect. A strong positive correlation was found between professor and candidate regarding the tested activity indices (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|