Feeding response to central orexins

Autor: Allen S. Levine, Charles J. Billington, Catherine M. Kotz, Donald C. Sweet
Rok vydání: 1999
Předmět:
Zdroj: Brain Research. 821:535-538
ISSN: 0006-8993
DOI: 10.1016/s0006-8993(99)01136-1
Popis: Orexin A and orexin B were microinjected into the perifornical hypothalamus (PFH), lateral hypothalamus (LH), hypothalamic paraventricular nucleus (PVN), and ventral tegmental area (VTA) of male Sprague–Dawley rats. Orexin B (15 nmol) was also injected into the lateral cerebral ventricle (i.c.v.). Orexin A (≥500 pmol) stimulated feeding in the PFH and LH, but not in the VTA or PVN. Orexin B stimulated feeding only when injected i.c.v.
Databáze: OpenAIRE