Successful renal transplantation from a brain-dead deceased donor with head injury, disseminated intravascular coagulation and deranged renal functions
| Autor: | Pankaj R Shah, V B Kute, H L Trivedi, Manoj R. Gumber, DN Gera, P P Ghuge, Pranjal R Modi, Veena R Shah, Himanshu V Patel, A V Vanikar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Disseminated intravascular coagulation
medicine.medical_specialty Deceased donor business.industry Incidence (epidemiology) Head injury Renal function Case Report medicine.disease lcsh:Diseases of the genitourinary system. Urology lcsh:RC870-923 Surgery Transplantation Nephrology hemic and lymphatic diseases renal transplant medicine Organ donation business Contraindication disseminated intravascular coagulation circulatory and respiratory physiology |
| Zdroj: | Indian Journal of Nephrology, Vol 23, Iss 6, Pp 448-451 (2013) Indian Journal of Nephrology |
| ISSN: | 1998-3662 0971-4065 |
| Popis: | Deceased donors (DDs) with the brain death due to head injury are the major source of organs for transplantation. The incidence of post-head injury disseminated intravascular coagulation (DIC) ranges from 24% to 50%. Many centers do not accept organs from donors with DIC due to increased risk of primary graft non-function and/or high chances of morbidity/mortality. We performed two successful renal transplants from a DD with head injury with DIC and deranged renal function. One of the recipients developed transient thrombocytopenia, but there was no evidence of DIC or delayed graft functions in either of the recipients. Over a follow-up of 1 month, both are doing well with stable graft function and hematological profile. Thus, a carefully selected DD with severe DIC even with deranged renal function is not a contraindication for organ donation if other risk factors for primary non-function are excluded. This approach will also help in overcoming organ shortage. |
| Databáze: | OpenAIRE |
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