Dairy foods, calcium, and risk of breast cancer overall and for subtypes defined by estrogen receptor status: a pooled analysis of 21 cohort studies
| Autor: | Elisabete Weiderpass, Anna E. Prizment, Rachael Z. Stolzenberg-Solomon, Stephanie A. Smith-Warner, Sabina Sieri, Gretchen L. Gierach, Susanna C. Larsson, Shoichiro Tsugane, Roger L. Milne, Norie Sawada, Alicja Wolk, Anne Zeleniuch-Jacquotte, Chu Chen, You Wu, Linda M. Liao, Marian L. Neuhouser, Sven Sandin, Julie R. Palmer, Marjorie L. McCullough, Graham G. Giles, Vittorio Krogh, Neal D. Freedman, A. Heather Eliassen, Walter C. Willett, Leslie Bernstein, Peggy Reynolds, Yu Chen, Anthony B. Miller, Lynne R. Wilkens, Regina G. Ziegler, Ruyi Huang, Traci N. Bethea, Rashmi Sinha, Piet A. van den Brandt, Molin Wang, Thomas E. Rohan, Kristine R. Monroe, Mia M. Gaudet, Kim Robien, Kala Visvanathan |
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| Přispěvatelé: | RS: GROW - R1 - Prevention, RS: CAPHRI - R5 - Optimising Patient Care, Epidemiologie |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Oncology MILK CONSUMPTION Medicine (miscellaneous) Estrogen receptor Cohort Studies CONFIDENCE-INTERVALS 0302 clinical medicine Risk Factors VITAMIN-D Estrogen Receptor Status milk Nutrition and Dietetics Hazard ratio WOMEN LOGISTIC-REGRESSION DIETARY PATTERNS Original Research Communications Receptors Estrogen 030220 oncology & carcinogenesis Female pooled analysis Cohort study medicine.medical_specialty chemistry.chemical_element Breast Neoplasms Calcium VALIDATION cheese 03 medical and health sciences yogurt Breast cancer breast cancer Internal medicine medicine Vitamin D and neurology Humans FREQUENCY QUESTIONNAIRE METAANALYSIS calcium business.industry dairy products Cancer medicine.disease PREVENTION 030104 developmental biology chemistry Multivariate Analysis business diet |
| Zdroj: | Am J Clin Nutr American Journal of Clinical Nutrition, 114(2), 450-461. Oxford University Press |
| ISSN: | 0002-9165 |
| Popis: | BACKGROUND: Epidemiologic studies examining the relations between dairy product and calcium intakes and breast cancer have been inconclusive, especially for tumor subtypes. OBJECTIVE: To evaluate the associations between intakes of specific dairy products and calcium and risk of breast cancer overall and for subtypes defined by estrogen receptor (ER) status. METHOD: We pooled the individual-level data of over 1 million women who were followed for a maximum of 8–20 years across studies. Associations were evaluated for dairy product and calcium intakes and risk of incident invasive breast cancer overall (n = 37,861 cases) and by subtypes defined by ER status. Study-specific multivariable hazard ratios (HRs) were estimated and then combined using random-effects models. RESULTS: Overall, no clear association was observed between the consumption of specific dairy foods, dietary (from foods only) calcium, and total (from foods and supplements) calcium, and risk of overall breast cancer. Although each dairy product showed a null or very weak inverse association with risk of overall breast cancer (P, test for trend >0.05 for all), differences by ER status were suggested for yogurt and cottage/ricotta cheese with associations observed for ER-negative tumors only (pooled HR = 0.90, 95% CI: 0.83, 0.98 comparing ≥60 g/d with |
| Databáze: | OpenAIRE |
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