Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
| Autor: | Andreina Garcia-de-Frenza, Ignacio Fernandez-Asian, Celia Vazquez-Pachon, José-Luis Gutiérrez-Pérez, María Rizo-Gorrita, Daniel Torres-Lagares, María-Ángeles Serrera-Figallo |
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| Přispěvatelé: | Ziacom Medical |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Bone density
Bone-Implant Interface medicine.medical_treatment Bone–implant interface lcsh:Technology Osseointegration lcsh:Chemistry 03 medical and health sciences 0302 clinical medicine Surface roughness In vivo medicine General Materials Science Viability assay titanium Dental implant lcsh:QH301-705.5 Instrumentation Fluid Flow and Transfer Processes Titanium Dental implant surfaces lcsh:T Chemistry Process Chemistry and Technology General Engineering osseointegration Osteoblast 030206 dentistry lcsh:QC1-999 Computer Science Applications bone–implant interface medicine.anatomical_structure lcsh:Biology (General) lcsh:QD1-999 lcsh:TA1-2040 030220 oncology & carcinogenesis surface roughness Implant lcsh:Engineering (General). Civil engineering (General) dental implant surfaces lcsh:Physics Biomedical engineering |
| Zdroj: | Applied Sciences Volume 10 Issue 14 idUS: Depósito de Investigación de la Universidad de Sevilla Universidad de Sevilla (US) Applied Sciences, Vol 10, Iss 4790, p 4790 (2020) idUS. Depósito de Investigación de la Universidad de Sevilla instname Digital.CSIC. Repositorio Institucional del CSIC |
| Popis: | © 2020 by the authors. The chemical composition and the surface characteristics of dental implants are factors that have a decisive effect on the osseointegration process. The surface characterization at the compositional and topographic level of three dental implants available in the market was performed with different surface treatments: (1) sandblasted and acid etched surface (SLA), (2) hydroxyapatite (HA) and tricalcium phosphate (TCP) blasted surface (HA/TCP), and (3) HA-blasted and non-etching acid washed surface (HA + AW). In addition, an in vitro viability study of MG-63 osteoblast cells was performed with a JC-1 test. To complete the study, an in vivo study was conducted in New Zealand rabbits. The study analyzed the histometric characteristics of the bone formed around the implants at the level of area, volume, bone density, accumulated bone density, and bone–implant contact (BIC). The rabbits were sacrificed at 6 weeks after implants were placed in the tibial metaphysis. No statistically significant differences were observed at the level of cell viability or histometric parameters between the different study groups (p > 0.05). SLA and HA/TCP surfaces were the ones that obtained a higher BIC value. Taking into account the limitations of this study, it can be concluded that the different implant surfaces analyzed favor a good bone response. This research was funded by Ziacom Medical SLU® (Madrid, Spain)—Grant FISEVI 2017. |
| Databáze: | OpenAIRE |
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