Genome reorganization in F 1 hybrids uncovers the role of retrotransposons in reproductive isolation
| Autor: | François Felber, Christian Parisod, Natacha Senerchia |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0106 biological sciences
Transposable element Reproductive Isolation Retroelements Retrotransposon Poaceae 01 natural sciences Genome General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Amplified Fragment Length Polymorphism Analysis Research Articles 030304 developmental biology General Environmental Science Hybrid Genetics 0303 health sciences General Immunology and Microbiology biology Terminal Repeat Sequences General Medicine Reproductive isolation biology.organism_classification Long terminal repeat Aegilops Hybridization Genetic Amplified fragment length polymorphism General Agricultural and Biological Sciences Genome Plant 010606 plant biology & botany |
| Zdroj: | Proceedings of the Royal Society of London. Series B Proceedings of the Royal Society B-Biological Sciences |
| ISSN: | 1471-2954 0962-8452 |
| DOI: | 10.1098/rspb.2014.2874 |
| Popis: | Interspecific hybridization leads to new interactions among divergent genomes, revealing the nature of genetic incompatibilities having accumulated during and after the origin of species. Conflicts associated with misregulation of transposable elements (TEs) in hybrids expectedly result in their activation and genome-wide changes that may be key to species boundaries. Repetitive genomes of wild wheats have diverged under differential dynamics of specific long terminal repeat retrotransposons (LTR-RTs), offering unparalleled opportunities to address the underpinnings of plant genome reorganization by selfish sequences. Using reciprocal F 1 hybrids between three Aegilops species, restructuring and epigenetic repatterning was assessed at random and LTR-RT sequences with amplified fragment length polymorphism and sequence-specific amplified polymorphisms as well as their methylation-sensitive counterparts, respectively. Asymmetrical reorganization of LTR-RT families predicted to cause conflicting interactions matched differential survival of F 1 hybrids. Consistent with the genome shock model, increasing divergence of merged LTR-RTs yielded higher levels of changes in corresponding genome fractions and lead to repeated reorganization of LTR-RT sequences in F 1 hybrids. Such non-random reorganization of hybrid genomes is coherent with the necessary repression of incompatible TE loci in support of hybrid viability and indicates that TE-driven genomic conflicts may represent an overlooked factor supporting reproductive isolation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|