Preoperative intra-aortic balloon pump improves the clinical outcomes of off-pump coronary artery bypass grafting in left ventricular dysfunction patients
| Autor: | Xiaotong Hou, Jialin Xing, Chengxiong Gu, Yanyan Zhao, Zhongtao Du, Li-Zhong Sun, Feng Liu, Zhi chen Xing, Xing Hao, Jinhong Wang, Chunjing Jiang, Dengbang Hou, Hong Wang, Xiaofang Yang, Na Miao, Yu Jiang, Ran Dong, Feng Yang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment 030204 cardiovascular system & hematology Intra-Aortic Balloon Pumping Article 03 medical and health sciences Ventricular Dysfunction Left 0302 clinical medicine Postoperative Complications Internal medicine medicine Humans Coronary Artery Bypass Off-pump coronary artery bypass Intra-aortic balloon pump Aged Mechanical ventilation Multidisciplinary Ejection fraction business.industry 030208 emergency & critical care medicine Retrospective cohort study Length of Stay Middle Aged Respiration Artificial Surgery medicine.anatomical_structure Preoperative Period Cardiology Observational study Female business Artery |
| Zdroj: | Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | Severe left ventricular (LV) dysfunction patients undergoing off-pump coronary artery bypass grafting (OPCAB) are often associated with a higher mortality. The efficacy and safety of the preoperative prophylactic intra-aortic balloon pump (IABP) insertion is not well established. 416 consecutive patients with severe LV dysfunction (ejection fraction ≤35%) undergoing isolated OPCAB were enrolled in a retrospective observational study. 191 patients was enrolled in the IABP group; the remaining 225 patients was in control group. A total of 129 pairs of patients were propensity-score matched. No significant differences in demographic and preoperative risk factors were found between the two groups. The postoperative 30-day mortality occurred more frequently in the control group compared with the IABP group (8.5% vs. 1.6%, p = 0.02). There was a significant reduction of low cardiac output syndrome in the IABP group compared with the control group (14% vs. 6.2%, p = 0.04). Prolonged mechanical ventilation (≥48 h) occurred more frequently in the control group (34.9% vs. 20.9%, p = 0.02). IABP also decreased the postoperative length of stay. Preoperative IABP was associated with a lower 30-day mortality, suggesting that it is effective in patients with severe LV dysfunction undergoing OPCAB. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|