Graves' Disease: A Long-Term Quality-of-Life Follow Up of Patients Randomized to Treatment with Antithyroid Drugs, Radioiodine, or Surgery
| Autor: | Göran Wallin, Bertil Hamberger, Mirna Abraham-Nordling, Ove Tørring, Leif Tallstedt, Jan Calissendorff, Göran Lundell |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Randomization Endocrinology Diabetes and Metabolism medicine.medical_treatment Graves' disease Thyrotropin Disease law.invention Iodine Radioisotopes Endocrinology Antithyroid Agents Quality of life Randomized controlled trial Recurrence law Surveys and Questionnaires medicine Humans Social Behavior Sweden business.industry Medical record Thyroidectomy Middle Aged medicine.disease Mental health Graves Disease Surgery Mental Health Health Quality of Life Female business Follow-Up Studies |
| Zdroj: | Thyroid. 15:1279-1286 |
| ISSN: | 1557-9077 1050-7256 |
| Popis: | The effects of treatment modality for Graves' disease (GD) were studied with respect to long-term quality of life and present health status. A total of 179 patients with GD were randomized during the period 1983-1990 for treatment with antithyroid drugs, radioiodine, or surgery. A 36-item Short Form Health Status Survey questionnaire and specific questions for GD were sent to patients 14-21 years after randomization. Present medical records, and clinical and laboratory status were recorded. No major significant differences in quality of life among the three treatments were observed. Compared to a large Swedish reference group, all treatment groups had significantly lower scores for vitality (p < 0.05). The Mental Component Summary was lower for both the young medical, young surgical, and the older medical group (p < 0.05). Radioiodine-treated patients had a lower General Health score. Young medical patients ( |
| Databáze: | OpenAIRE |
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