Disposable Stochastic Sensors Based on Nanolayer Deposition(s) of Silver and AgC Composite on Plastic for the Assay of α-amylase in Whole Blood and Saliva

Autor: Alexandrina Moscalu-Lungu, Marius Badulescu, Raluca-Ioana Stefan-van Staden
Rok vydání: 2020
Předmět:
Zdroj: Nanomaterials
Volume 10
Issue 8
Nanomaterials, Vol 10, Iss 1528, p 1528 (2020)
ISSN: 2079-4991
Popis: Nanolayer deposition(s) of Ag and AgC composite on a plastic substrate was used to design disposable stochastic sensors. Three shapes of nanocoatings were tested. The first shape was obtained by deposition of a nanofilm of Ag on the plastic material
the second shape was obtained by deposition of a composite AgC nanolayer on the plastic material
the third shape was obtained by nanolayer deposition of a composite material of AgC on the top of the Ag nanofilm deposited on the plastic material. &alpha
Cyclodextrin was used to modify the active surface of the sensor. Wide linear concentration ranges were obtained as follows: for de-assay of &alpha
amylase in whole blood: 1.00 ×
10&minus
7&ndash
1.00 ×
103 U mL&minus
1 and for the assay of &alpha
amylase in saliva: 1.5 ×
15&ndash
1.5 ×
102 U mL&minus
1. &alpha
Amylase was reliably determined from whole blood and saliva samples using the proposed disposable stochastic sensors.
Databáze: OpenAIRE