The Lung Function Impairment in Non-Atopic Patients With Chronic Rhinosinusitis and Its Correlation Analysis
| Autor: | Zhi-Su Liao, Lu Zhang, Qing-yuan Shi, Li-ping Wu, Peng Wu, Linghao Zhang, Zhen-xiao Huang, Zhen-zhen Wang, Chun-Hong Zhang, Xiao-bi Fang |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Pathology Vital capacity Chronic rhinosinusitis Visual analogue scale lcsh:Medicine Gastroenterology Bronchial Provocation Tests 03 medical and health sciences 0302 clinical medicine Lung Function Internal medicine Chronic Rhinosinusitis medicine otorhinolaryngologic diseases Nasal polyps 030223 otorhinolaryngology Lung function business.industry lcsh:R Eosinophil respiratory system lcsh:Otorhinolaryngology medicine.disease lcsh:RF1-547 medicine.anatomical_structure 030228 respiratory system Otorhinolaryngology Surgery Original Article Bronchial Hyperreactivity business Airway |
| Zdroj: | Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology, Vol 9, Iss 4, Pp 339-345 (2016) |
| ISSN: | 1976-8710 |
| Popis: | Objectives Chronic rhinosinusitis (CRS) is common disease in otorhinolaryngology and will lead to lower airway abnormality. However, the only lung function in CRS patients and associated factors have not been much studied. Methods One hundred patients with CRS with nasal polyps (CRSwNP group), 40 patients with CRS without nasal polyps (CRSsNP group), and 100 patients without CRS were enrolled. The difference in lung function was compared. Meanwhile, CRSwNP and CRSsNP group were required to undergo a bronchial provocation or dilation test. Additionally, subjective and objective outcomes were measured by the visual analogue scale (VAS), 20-item Sino-Nasal Outcome Test (SNOT-20), Lund-Mackay score, Lund-Kennedy endoscopic score. The correlation and regression methods were used to analyze the relationship between their lung function and the above parameters. Results The forced expiratory volume in 1 second (FEV1) and forced expiratory flow between 25% and 75% of forced vital capacity (FEF25-75) of CRSwNP group were significantly lower than other groups (P |
| Databáze: | OpenAIRE |
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