Shunting normal-pressure hydrocephalus: do the benefits outweigh the risks? A multicenter study and literature review
| Autor: | J. Vanneste, Wee Fu Tan, P. Augustijn, Z. D. Goedhart, C. Dirven |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Reoperation medicine.medical_specialty Normal pressure hydrocephalus Cerebrospinal Fluid Pressure Risk Factors medicine Humans Derivation Aged Aged 80 and over business.industry Mortality rate Incidence (epidemiology) Retrospective cohort study Middle Aged medicine.disease Cerebrospinal Fluid Shunts Hydrocephalus Normal Pressure Surgery Hydrocephalus Evaluation Studies as Topic Female Neurology (clinical) Cerebrospinal fluid pressure Morbidity business Complication |
| Zdroj: | Neurology. 42(1) |
| ISSN: | 0028-3878 |
| Popis: | We performed a multicenter retrospective study in 166 consecutive patients shunted for presumed normal-pressure hydrocephalus (NPH) in the four neurosurgical departments of Amsterdam. Overall improvement occurred in 36%, substantial improvement in 21%. In the subgroup of idiopathic NPH (N = 127), marked improvement was only 15%. The incidence of shunt-responsive NPH in our area was 2.2/million/year. The rate of severe and moderate shunt-related complications was 28%, leading to death or severe residual morbidity in 7%. The substantial benefit/serious harm ratio in the whole group was only three (21%/7%), decreasing to 1.7 in idiopathic NPH. By excluding patients at high surgical risk, this ratio might have risen to 10 in the whole group and to six in idiopathic NPH. Our experience is much less favorable than that encountered in the literature, reporting overall improvement in 74% and marked improvement in 55% of the shunted patients. We conclude that NPH is probably a very rare and still overdiagnosed syndrome and that the overall morbidity rate for each patient demonstrating meaningful improvement is high. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|