Increased Urinary Albumin Excretion Rate in Breast Cancer Patients
| Autor: | Lars Møller Pedersen, Peter Grundtvig Sørensen |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Oncology medicine.medical_specialty Breast Neoplasms Urine Sensitivity and Specificity Gastroenterology Breast cancer Predictive Value of Tests Internal medicine Biomarkers Tumor medicine Albuminuria Humans Radiology Nuclear Medicine and imaging Neoplasm Metastasis Prospective cohort study Survival rate Survival analysis Aged Aged 80 and over business.industry Hematology General Medicine Middle Aged Prognosis medicine.disease Metastatic breast cancer Predictive value of tests Female Microalbuminuria business |
| Zdroj: | Acta Oncologica. 39:145-149 |
| ISSN: | 1651-226X 0284-186X |
| DOI: | 10.1080/028418600430699 |
| Popis: | A high frequency of slightly increased urinary albumin excretion (UAE) has been reported in patients with malignancies. Earlier studies have indicated a prognostic significance of UAE in some malignant diseases. We measured urinary albumin in 24-h urine samples in 44 patients with newly diagnosed early breast cancer and in 22 patients with relapse of metastatic breast cancer disease. The prevalence of microalbuminuria ( > or = 20 microg/min) was 20.5% in patients with early breast cancer and 54.5% in patients with metastatic disease. Median UAE was significantly higher in patients with metastatic breast cancer compared with the early breast cancer group (20.5 microg/min vs. 9.2 microg/min; p < 0.01). In patients with metastatic breast cancer, univariate survival analysis revealed a significantly lower survival rate in patients with microalbuminuria compared with the normoalbuminuric group (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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