Smoking, Alcohol Drinking, Green Tea Consumption and the Risk of Esophageal Cancer in Japanese Men
| Autor: | Yoshitaka Tsubono, Atsunobu Ishikawa, Hidekiyo Tachiya, Ichiro Tsuji, Akira Fukao, Haruhiko Takahashi, Shinichi Kuriyama |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Risk
Adult Male medicine.medical_specialty Alcohol Drinking Esophageal Neoplasms Epidemiology Population Cohort Studies Japan Risk Factors Environmental health medicine Humans education Prospective cohort study Proportional Hazards Models education.field_of_study Tea Proportional hazards model business.industry Incidence (epidemiology) Hazard ratio Smoking Cancer General Medicine Middle Aged medicine.disease Surgery Cohort Original Article business Cohort study |
| Zdroj: | Journal of Epidemiology |
| ISSN: | 1349-9092 0917-5040 |
| Popis: | BACKGROUND: Although smoking and alcohol drinking are established risk factors of esophageal cancer, their public health impact is unclear. Furthermore, the effect of green tea is controversial.METHODS: The present study was based on a pooled analysis of two prospective cohort studies. A self-administered questionnaire about health habits was distributed to 9,008 men in Cohort 1 and 17,715 men in Cohort 2, aged 40 years or older, with no previous history of cancer. We identified 38 and 40 patient cases with esophageal cancer among the subjects in Cohort 1 (9.0 years of follow-up) and Cohort 2 (7.6 years of follow-up), respectively. Cox proportional hazards regression was used to estimate hazard ratios (HRs) of the risk of esophageal cancer incidence.RESULTS: Cigarette smoking, alcohol drinking and green tea consumption were significantly associated with an increased risk of esophageal cancer. Compared with men who had never smoked, never drunk alcohol or green tea, the pooled multivariate HRs (95% confidence intervals) were 5.09 (1.80-14.40) (p for trend |
| Databáze: | OpenAIRE |
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