Effect of nitrous oxide on middle ear pressure: a comparison between inhalational anaesthesia with nitrous oxide and TIVA

Autor: Celebi H, Lale Karabiyik, Bozkirli F, Göksu N
Rok vydání: 1996
Předmět:
Zdroj: European journal of anaesthesiology. 13(1)
ISSN: 0265-0215
Popis: We have investigated the effect of nitrous oxide on the middle ear pressure, comparing inhalational anaesthesia with nitrous oxide and halothane and total intravenous anaesthesia with propofol-alfentanil. Fifty patients with normal healthy ears were divided into two groups. In one group (n=25), anaesthesia was induced with thiopentone 6 mg kg(-1), and maintained with halothane 1% and nitrous oxide 66% in oxygen. In the other group (n=25), anaesthesia was induced with alfentanil 25 mu g kg(-1) and propofol 2 mg kg(-1), and maintained with an infusion of alfentanil 10 mu g kg(-1) min(-1) for the first 10 min and then with 0.5 mu g kg(-1) min(-1) and with propofol 10 mg kg(-1) h(-1) for the first 10 min, 8 mg kg(-1) h(-1) for the following 10 min and 6 mg kg(-1) h(-1) thereafter. Patients were ventilated with an oxygen-air mixture (F1O2=0.33). Middle ear pressures were measured during the pre-, intra- and post-anaesthetic period in both ears. A progressive rise was observed (P
Databáze: OpenAIRE