Recommendations for the management and treatment of systemic sclerosis

Autor: Percival Degrava, Sampaio-Barros, Adriana Fontes, Zimmermann, Carolina de Souza, Müller, Cláudia Tereza Lobato, Borges, Eutília Andrade Medeiros, Freire, Giselle Baptista, Maretti, João Francisco, Marques Neto, Maria Cecília Fonseca, Salgado, Maria de Fátima Lobato da Cunha, Sauma, Mário Newton Leitão, de Azevedo, Sheila, Fontenelle, Cristiane, Kayser
Rok vydání: 2013
Předmět:
Zdroj: Revista Brasileira de Reumatologia (English Edition). 53:258-275
ISSN: 2255-5021
DOI: 10.1016/s2255-5021(13)70032-4
Popis: Description of the method to elaborate the evidenceThe members of the Comissão de Esclerose Sistêmica da Sociedade Brasileira de Reumatologia (Systemic Sclerosis Commission of the Brazilian Society of Rheumatology, SBR) 2010- 2012 took part in the Evidence Preparation Course given by the Associação Médica Brasileira (Brazilian Medical Association, AMB) in São Paulo in the first semester of 2011. The questions were formulated and discussed via internet in the second semester of 2011. The 15 clinical questions considered to be relevant were structured using the P.I.C.O. method (patient; intervention or indicator; comparison; outcome). The literature search was conducted by searching the databases MEDLINE, EMBASE, SciElo/Lilacs, and the Cochrane Library through February, 2012 (Appendix). Critical assessment of the evidence in the selected articles was performed using the Jadad score. The observational studies and case series were considered for analysis when randomised clinical trials could not be located. A manual search located the relevant studies that were included in the analysis. The answers to the questions included in the Recommendations were refined and elaborated, and all of the selected references exhibited the corresponding grade of recommendation and the strength of scientific evidence. The references were updated through December, 2012, entered into a single file by the coordinator, and sent to the co-authors in four successive rounds for preparation of the final version.Grades of recommendation and strength of evidenceA.Most consistent experimental and observational studies.B.Less consistent experimental and observational studies.C.Case reports (uncontrolled studies).D.Opinion that is not substantiated by critical evaluation, based on consensus, physiological studies or animal models.ObjectiveTo establish recommendations for the management and treatment of systemic sclerosis.
Databáze: OpenAIRE