Evaluating meaningful levels of financial toxicity in gynecologic cancers
| Autor: | Lindsay Rucker, Katharine M. Esselen, Sarah S. Summerlin, Warner K. Huh, Meghan Shea, Sara Bouberhan, Maria Pisu, Margaret I. Liang, Michele R. Hacker, Annika Gompers |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Wilcoxon signed-rank test Genital Neoplasms Female Comprehensive Score for Financial Toxicity Financial Stress Gynecologic oncology 03 medical and health sciences symbols.namesake 0302 clinical medicine Humans Medicine 030212 general & internal medicine Poisson regression Aged Finance business.industry Obstetrics and Gynecology General Medicine Middle Aged Exact test Oncology 030220 oncology & carcinogenesis Relative risk Toxicity Cohort symbols Female business |
| Zdroj: | International Journal of Gynecologic Cancer. 31:801-806 |
| ISSN: | 1525-1438 1048-891X |
| DOI: | 10.1136/ijgc-2021-002475 |
| Popis: | ObjectiveThe Comprehensive Score for Financial Toxicity (COST) is a validated instrument measuring the economic burden experienced by patients with cancer. We evaluated the frequency of financial toxicity at different COST levels and stratified risk factors and associations with cost-coping strategies by financial toxicity severity.MethodsWe analyzed previously collected survey data of gynecologic oncology patients from two tertiary care institutions. Both surveys included the COST tool and questions assessing economic and behavioral cost-coping strategies. We adapted a proposed grading scale to define three groups: no/mild, moderate, and severe financial toxicity and used χ2, Fisher’s exact test, and Wilcoxon rank sum test to compare groups. We used Poisson regression to calculate crude and adjusted risk ratios for cost-coping strategies, comparing patients with moderate or severe to no/mild financial toxicity.ResultsAmong 308 patients, 14.9% had severe, 32.1% had moderate, and 52.9% had no/mild financial toxicity. Younger age, non-white race, lower education, unemployment, lower income, use of systemic therapy, and shorter time since diagnosis were associated with worse financial toxicity (all pConclusionsAmong a geographically diverse cohort of gynecologic oncology patients, nearly half reported financial toxicity (COST |
| Databáze: | OpenAIRE |
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