Intractable diarrhoea in infancy in the 1990s: a survey in Italy

Autor: A. Ventura, D. Dragovich, N. Ansaldi, F. Balli, G. Banchini, F. Bascietto, C. Bianchi, M. Bonamico, M. Calvani, E. Ciardi, M. Castro, F. Cataldo, C. Catassi, C. ughi, M. Ciampolini, A. dore, L. De Seta, D. Faraguna, R. Ferrari, M. Fontana, A. M. Giunta, S. Guandalini, G. Iacono, A. Lambertini, R. Lazzari, G. Mastella, A. Miano, R. Patanè, F. Pesce, P. roggero, V. Rutigliano, S. Scotta, A. Tedeschi, R. Troncone, A. ugazio, L. Zancan, GUARINO, ALFREDO
Přispěvatelé: A., Ventura, D., Dragovich, N., Ansaldi, F., Balli, G., Banchini, F., Bascietto, C., Bianchi, M., Bonamico, M., Calvani, E., Ciardi, M., Castro, F., Cataldo, C., Catassi, C., Ughi, M., Ciampolini, A., Dore, L., De Seta, D., Faraguna, R., Ferrari, M., Fontana, A. M., Giunta, S., Guandalini, Guarino, Alfredo, G., Iacono, A., Lambertini, R., Lazzari, G., Mastella, A., Miano, R., Patanè, F., Pesce, P., Roggero, V., Rutigliano, S., Scotta, A., Tedeschi, R., Troncone, A., Ugazio, L., Zancan
Rok vydání: 1995
Předmět:
Popis: A "quick" prevalence study of intractable diarrhoea (defined as diarrhoea lasting more than 3 weeks and dependent on parenteral nutrition [PN] for more than 50% of daily caloric intake) was conducted by FAX. All 35 paediatric gastroenterology services which had been contacted answered questionnaire sent by FAX. 20 cases of intractable diarrhoea were identified in 9 centres. In 12 cases PN was administered at home, the other 8 cases being treated as inpatients for an average duration of 9.5 months. A diagnosis had been established in 11 out of 20 cases. Auto-immune enteropathy was the most frequent diagnosis (5 cases); congenital microvillous atrophy (3 cases); chronic pseudo-obstruction (2 cases) and multiple food intolerance (1 case). Undefined 9/20 cases presented atrophy of intestinal mucosa. The age of the beginning of diarrhoea varied from 2 days to 12 years, but was more than 16 months only in some cases with auto-immune enteropathy. CONCLUSION: Intractable diarrhoea has a low prevalence in Italy and remains a rare but very intricating problem. Long-term PN is recommended in most cases: autoimmune enteropathy is the most frequent cause but in about half of the cases the aetiopathogenetic diagnosis is still not defined.
Databáze: OpenAIRE