Hepatic Elastometry and Glissonian Line in the Assessment of Liver Fibrosis
| Autor: | Antonino Picciotto, I. Baldissarro, Paolo Borro, Simona Marenco, Sara Labanca, Marco Trombini, Silvana Dellepiane, Sebastiano Ziola, Livia Pisciotta, Andrea Pasta, David Solarna |
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| Rok vydání: | 2021 |
| Předmět: |
Liver Cirrhosis
Male Transient elastography Acoustics and Ultrasonics Biopsy Liver fibrosis Fibrosis staging Biophysics Anterior margin Pilot Projects 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Image Processing Computer-Assisted Humans Neural networks Medicine Radiology Nuclear Medicine and imaging Radiological and Ultrasound Technology Receiver operating characteristic business.industry Left lobe Ultrasound Middle Aged ROC Curve Area Under Curve Elasticity Imaging Techniques Female 030211 gastroenterology & hepatology Neural Networks Computer Ultrasonography business Hepatic fibrosis Nuclear medicine Software |
| Zdroj: | Ultrasound in Medicine & Biology. 47:947-959 |
| ISSN: | 0301-5629 |
| Popis: | The aim of this study was to identify a method for staging hepatic fibrosis using a non-invasive, rapid and inexpensive technique based on ultrasound morphologic hepatic features. A total of 215 patients with different liver diseases underwent B-mode (2-D brightness mode) ultrasonography, vibration-controlled transient elastography, 2-D shear wave elastography and measurement of the controlled attenuation parameter with transient elastography. B-Mode images of the anterior margin of the left lobe were obtained and processed with automatic Genoa Line Quantification (GLQ) software based on a neural network for staging liver fibrosis. The accuracy of GLQ was 90.6% during model training and 78.9% in 38 different patients with concordant elastometric measures. Receiver operating characteristic curve analysis of GLQ performance using vibration-controlled transient elastography as a reference yielded areas under the curves of 0.851 for F ≥ F1, 0.793 for F ≥ F2, 0.784 for F ≥ F3 and 0.789 for F ≥ F4. GLQ has the potential to be a rapid, easy-to-perform and tolerable method in the staging of liver fibrosis. |
| Databáze: | OpenAIRE |
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