[Restoration of Sinus Rhythm in Patients With Persistent Atrial Fibrillation and Obesity: New Possibilities of Pharmacological Cardioversion]
| Autor: | E I Chazov, V. V. Vlodzyanovskiy, S. F. Sokolov, Sergey P. Golitsyn, T A Malkina, M A Saidova, Rozenshtraukh Lv |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry Electric Countershock Severe obesity medicine.disease Obesity Electrical cardioversion Internal medicine Persistent atrial fibrillation Atrial Fibrillation Cardiology medicine Pharmacological cardioversion Humans Sinus rhythm In patient Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents |
| Zdroj: | Kardiologiia. 57(10) |
| ISSN: | 0022-9040 |
| Popis: | We present in this article 2 cases of successful pharmacological restoration of sinus rhythm by a new class III antiarrhythmic drug refralon in patients with obesity and persistent atrial fibrillation. In both cases, the effective use of refralon was preceded by repeated ineffective attempts of electrical cardioversion. In the article we discuss the role of obesity as the factor leading to a substantial increase of transthoracic electrical resistance, and thus significantly reducing the probability of sinus rhythm restoration by means of electrical cardioversion. The clinical examples described in this article clearly show that the use of refralon may represent a unique clinical alternative to electrical cardioversion for sinus rhythm restoration in patients with persistent atrial fibrillation, and in some cases where the success of electrical cardioversion is obviously questionable, like in patients with severe obesity, the use of refralon seems preferable. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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