Immobilization of Chiral Ligands on Polymer Fibers by Electron Beam Induced Grafting and Applications in Enantioselective Catalysis

Autor:	Reko Leino, Sylvestre Degni, Carl-Eric Wilén
Rok vydání:	2001
Předmět:	Chemistry Comonomer Organic Chemistry Enantioselective synthesis Diethylzinc Polyethylene Photochemistry Biochemistry Catalysis Styrene Benzaldehyde chemistry.chemical_compound Physical and Theoretical Chemistry Enantiomer
Zdroj:	Organic Letters. 3:2551-2554
ISSN:	1523-7052 1523-7060
DOI:	10.1021/ol016212y
Popis:	[reaction: see text] Styrenic TADDOL and L-prolinol-derived monomers were immobilized on polyethylene fibers by electron beam induced preirradiation grafting using styrene as comonomer. The polymer-supported chiral ligands were utilized as catalysts in the asymmetric addition of diethylzinc to benzaldehyde. Fiber-bound titanium TADDOLate gave a quantitative conversion of benzaldehyde to 1-phenylpropan-1-ol in a 97:3 S/R enantiomeric ratio. The catalyst was successfully regenerated and employed in subsequent reactions with retention of high enantioselectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0259720e7c55645a907ddceb44f0cd https://doi.org/10.1021/ol016212y Zobrazit plný text záznamu