Facile nucleophilic substitution of coordinated acetonitrile in trans-[PtCl4(NCMe)(PPh3)]
| Autor: | Laura Agnarelli, Daniela Belli Dell' Amico, Fabio Marchetti, Luca Labella, David Fioco, Simona Samaritani |
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| Rok vydání: | 2021 |
| Předmět: |
010405 organic chemistry
Quinoline chemistry.chemical_element trans effect 010402 general chemistry substitution reactions 01 natural sciences Medicinal chemistry triphenylphosphine 0104 chemical sciences Inorganic Chemistry chemistry.chemical_compound chemistry Benzothiazole Nucleophile platinum(IV) complexes Materials Chemistry Nucleophilic substitution Physical and Theoretical Chemistry Isoquinoline Chemoselectivity Platinum Acetonitrile |
| Popis: | Despite the generally accepted inertness of platinum(IV) complexes towards nucleophilic substitution, the title compound promptly reacts with nucleophiles L (L = pyridine, quinoline, isoquinoline, benzothiazole, o-, m-, p-toluidine) affording the corresponding acetonitrile substitution products. To follow the reaction spectroscopically, a series of platinum(IV) standards were prepared by bridge splitting of trans-[Pt(μ-Cl)Cl(PPh3)]2, followed by oxidation by PhICl2. All the new platinum(II) and platinum(IV) complexes were fully characterized, and, in some cases, the structure was studied by single crystal X-ray diffraction. Even when protic o-, m- and p-toluidines were used, chemoselectivity towards substitution was observed, with addition products formed in less than 10% extent. |
| Databáze: | OpenAIRE |
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