Lower Annual Rate of Progression of Short-Segment vs Long-Segment Barrett's Esophagus to Esophageal Adenocarcinoma
| Autor: | Neil Gupta, David A. Lieberman, Sreekar Vennelaganti, Srinivas Gaddam, Manon C.W. Spaander, Kevin F. Kennedy, Brooks D. Cash, Richard E. Sampliner, Marco J. Bruno, Sophie H. van Olphen, Prateek Sharma, Prashanth Vennalaganti, Patrick E. Young, Gary W. Falk, Ajay Bansal, Sharad C. Mathur, John J. Vargo, Sravanthi Parasa, Prashanthi N. Thota, Nour Hamade |
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| Přispěvatelé: | Gastroenterology & Hepatology |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Hepatology medicine.diagnostic_test business.industry Hazard ratio Gastroenterology Esophageal cancer medicine.disease Article Endoscopy 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Dysplasia 030220 oncology & carcinogenesis Barrett's esophagus Internal medicine Medicine 030211 gastroenterology & hepatology Risk factor Esophagus business Body mass index |
| Zdroj: | Clinical Gastroenterology and Hepatology, 17(5), 864-868. W.B. Saunders |
| ISSN: | 1542-7714 1542-3565 |
| Popis: | BACKGROUND & AIMS: European guidelines recommend different surveillance intervals of non-dysplastic Barrett’s esophagus (NDBE) based on segment length, as opposed to guidelines in the United States, which do recommend surveillance intervals based on BE length. We studied rates of progression of NDBE to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) in patients with short-segment BE using the definition of BE in the latest guidelines (length ≥1 cm). METHODS: We collected demographic, clinical, endoscopy, and histopathology data from 1883 patients with endoscopic evidence of NDBE (mean age, 57.3 years; 83.5% male; 88.1% Caucasians) seen at 7 tertiary referral centers. Patients were followed for a median 6.4 years. Cases of dysplasia or EAC detected within 1 year of index endoscopy were considered prevalent and were excluded. Unadjusted rates of progression to HGD or EAC were compared between patients with short (≥1 and |
| Databáze: | OpenAIRE |
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