Cyberlindnera jadinii (teleomorph Candida utilis) candidaemia in a patient with aplastic anaemia: a case report
| Autor: | Hélène Lanic, Vincent Camus, Stéphane Leprêtre, Gilles Gargala, Emilie Lemasle, Aspasia Stamatoullas, Marion David, Nathalie Contentin, Pascal Lenain, Hervé Tilly, Pauline Treguier, Anne-Lise Menard, Fabrice Jardin |
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| Přispěvatelé: | Génomique et Médecine Personnalisée du Cancer et des Maladies Neuropsychiatriques (GPMCND), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'hématologie, Centre de Lutte Contre le Cancer Henri Becquerel Normandie Rouen (CLCC Henri Becquerel), CHU Rouen, Normandie Université (NU), Epidémiosurveillance de protozooses à transmission alimentaire et vectorielle (ESCAPE), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Université de Reims Champagne-Ardenne (URCA), VILLIER, Venceslas, Université de Reims Champagne-Ardenne (URCA)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
[SDV.MHEP.HEM] Life Sciences [q-bio]/Human health and pathology/Hematology
Microbiology (medical) Antifungal medicine.medical_specialty medicine.drug_class Case Report Case presentation Microbiology Cyberlindnera 03 medical and health sciences 0302 clinical medicine medullary aplasia [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Internal medicine Medicine candidaemia Cyberlindnera jadinii Pichia Torulopsis utilis biology Adult patients business.industry Septic shock Blood/heart and Lymphatics [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology medicine.disease biology.organism_classification 3. Good health Transplantation 030220 oncology & carcinogenesis [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases business 030215 immunology |
| Zdroj: | JMM Case reports JMM Case reports, Society for General Microbiology, 2018, 5 (8), ⟨10.1099/jmmcr.0.005160⟩ JMM Case reports, 2018, 5 (8), ⟨10.1099/jmmcr.0.005160⟩ JMM Case Reports |
| ISSN: | 2053-3721 |
| Popis: | International audience; Introduction. We present what is believed to be the first report of candidaemia caused by Cyberlindnera (Pichia) jadinii (teleomorph of Candida utilis) in a patient with an aplastic anaemia.Case presentation. The patient, a 21-year-old male, presented with hepatic cytolysis, cutaneous and pulmonary involvement, and septic shock. Cyberlindnera jadinii was identified by aerobic blood culture and MS. The patient initially received multiple and combined antifungal therapy, but continued to have persistent skin lesions and fever. He was successfully treated by emergency haploidentical haematopoietic stem cell transplantation, combined with triple antifungal therapy and supportive care.Conclusion. Cyberlindnera jadinii, teleomorph of Candida utilis, which is not usually invasive, can lead to an opportunistic invasive infection in unhealthy adult patients. For treatment of the invasive candida infection, it is necessary to combine antifungal therapy and supportive care. |
| Databáze: | OpenAIRE |
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