Salivary Neutralizing Activity against Herpes Simplex Virus Type 1
| Autor: | R. Gyselink, M. E. Fritz, D. Coles, R. J. Ash |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Adult
Male Saliva viruses Antibodies Viral medicine.disease_cause Immunoglobulin G Neutralization Human immunoglobulin Neutralization Tests Clinical history Humans Simplexvirus Immunology and Allergy Medicine Antiserum biology business.industry Herpes Simplex Middle Aged Virology Infectious Diseases Herpes simplex virus Immunology biology.protein Female Antibody business |
| Zdroj: | Journal of Infectious Diseases. 137:583-586 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/137.5.583 |
| Popis: | Samples of saliva collected from 40 patients, of whom 16 had a previous clinical history of herpes simplex virus type 1 (HSV-1) infection, were concentrated and sterilized. Salivary neutralizing activity, as measured by a plaque-reduction method, was found in 62% of those patients with a history of oral lesions. Studies with antisera to human immunoglobulin indicated that the IgG class of immunoglobulin was a major HSV-1-neutralizing component of both saliva and serum. |
| Databáze: | OpenAIRE |
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