Imaging of IgG4-related disease in the extracranial head and neck
Autor: | Ravi Lingam, Alina Denisa Dragan, Alexander Weller |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Disease Autoimmune Diseases 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine parasitic diseases medicine Humans Radiology Nuclear Medicine and imaging Medical diagnosis Nose business.industry General Medicine Sinonasal Tract medicine.disease medicine.anatomical_structure Paranasal sinuses Immunoglobulin G 030220 oncology & carcinogenesis IgG4-related disease Immunoglobulin G4-Related Disease Radiology Differential diagnosis Presentation (obstetrics) business Head Neck |
Zdroj: | European Journal of Radiology. 136:109560 |
ISSN: | 0720-048X |
Popis: | Purpose Immunoglobulin G4-related disease (IgG4-RD) is a newly defined fibro-inflammatory multisystemic condition defined by a triad of diagnostic criteria based on clinical presentation, biochemical and histopathological findings. Whereas some subsites of this disease have been well described in the literature so far (e.g. pancreas, kidneys, retroperitoneum, salivary glands), more recently identified anatomical sites of involvement in the head and neck are less well understood (e.g. nose, paranasal sinuses). Method This pictorial review details the imaging appearances of extracranial IgG4-RD in the Head & Neck. Multimodality imaging appearance and features are presented, with reference to the published literature to date. Results Following a subsite-based approach, we present both the most common and the more rarely encountered imaging patterns of IgG4-RD in the extracranial head and neck, along with the relevant differential diagnoses to consider. Our institutional experience not only cements what is already known in the existing literature on this topic, but also reveals new imaging features of IgG4-RD, notably in the sinonasal tract. Conclusions This pictorial review of extracranial head & neck IgG4-RD will enable radiologists to recognise the features of this condition and propose it as a differential diagnosis to include alongside other probable entities. It establishes the place of the radiologist in the diagnosis and management of IgG4-RD. |
Databáze: | OpenAIRE |
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