Exercise Asthma and Disodium Cromoglycate

Autor: A. Muittari, Viljanen Aa, H. Poppius, O. Korhonen, K.-E. Kreus
Rok vydání: 1970
Předmět:
Zdroj: BMJ. 4:337-339
ISSN: 1468-5833
0959-8138
DOI: 10.1136/bmj.4.5731.337
Popis: Exercise-induced asthma (defined as a fall in PEF of at least 25% of the pre-exercise value) was studied in adult patients with uncomplicated asthma. This was found to occur in 22 out of 52 patients. Pre-exercise inhalation of disodium cromoglycate reduced the mean fall in PEF after maximal exercise from 50% of the pre-exercise value to 23% (open assessment in 11 cases). After submaximal exercise for eight minutes the reduction was from 18% to 10% (double-blind crossover study in 28 cases). It is concluded that disodium cromoglycate partly inhibits the increase of airways resistance after exercise in asthmatic patients.
Databáze: OpenAIRE