Monitoring the community use of antibiotics in Italy within the National Action Plan on antimicrobial resistance
| Autor: | Roberto Da Cas, Carlo Gagliotti, Federico Villa, Francesco Trotta, Agnese Cangini, Filomena Fortinguerra, Aurora Di Filippo, Maria Luisa Moro, Andrea Pierantozzi |
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| Rok vydání: | 2020 |
| Předmět: |
Drug Utilization
Adult Population 030226 pharmacology & pharmacy 03 medical and health sciences Young Adult 0302 clinical medicine Antibiotic resistance Environmental health Drug Resistance Bacterial Antimicrobial stewardship Medicine Humans Pharmacology (medical) 030212 general & internal medicine Medical prescription education Child Pharmacology Consumption (economics) education.field_of_study business.industry Incidence (epidemiology) Bacterial Infections Middle Aged Anti-Bacterial Agents Europe Defined daily dose Italy business |
| Zdroj: | British journal of clinical pharmacologyREFERENCES. 87(3) |
| ISSN: | 1365-2125 |
| Popis: | BACKGROUND In Italy both the consumption of antibiotics and the prevalence of bacterial resistance are higher than in other European countries. In 2017, the first National Action Plan on Antimicrobial Resistance (PNCAR) was adopted in Italy. In response to the PNCAR two national reports on antibiotic use in the human setting have been published. This article's aim is to describe the pattern of antibiotic consumption in the community setting in Italy from 2013 to 2018. METHODS To analyse the consumption for reimbursed antibiotics dispensed by community pharmacies different data sources were used. Consumption was measured in terms of defined daily dose (DDD), prescriptions or prevalence of use. RESULTS In 2018, the consumption of antibiotics in Italy amounted to 16.1 DDD per 1000 inhabitants per day. The rates of consumption by geographical area were: 12.7 DDD in the north, 16.9 in the centre and 20.4 in the south. The use was greater in the extreme age groups than in the population aged from 20 to 64 years. The consumption was higher in winter season, with high peaks in the incidence of flu syndromes. In the paediatric population, a utilization rate of 1010 prescriptions per 1000 children, with a prevalence of use of 40.8%, was found. CONCLUSION The study provides useful information on the geographical variability of antibiotic use in Italy to guide decision makers in the introduction of tailored interventions, as suggested by PNCAR, aimed at promoting a more rational use of antibiotics for humans and reducing antimicrobial resistance. |
| Databáze: | OpenAIRE |
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