Differences in Capacity of High-Amylose Resistant Starch, Whole-Grain Flour, and a Combination of Both to Modify Intestinal Responses of Male Sprague Dawley Rats Fed Moderate and High Fat Diets
| Autor: | Claudia Husseneder, Ryan Page, Michael J. Keenan, Diana Coulon, Anne M. Raggio, Christopher M. Taylor, Justin Guice, Maria L. Marco, Brian D. Marx, Zachary A. Bendiks, Meng Lou, David A. Welsh, Diana G. Carvajal-Aldaz |
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| Rok vydání: | 2020 |
| Předmět: |
Male
food.ingredient Flour Butyrate Diet High-Fat Whole grains Rats Sprague-Dawley Cecum Animal science food medicine Animals Resistant starch Intestinal Mucosa Barrier function chemistry.chemical_classification Gastrointestinal tract Whole Grains Resistant Starch General Chemistry Fatty Acids Volatile Rats Intestines medicine.anatomical_structure chemistry Gluconeogenesis Propionate Amylose General Agricultural and Biological Sciences |
| Zdroj: | Journal of agricultural and food chemistry. 68(51) |
| ISSN: | 1520-5118 |
| Popis: | Gastrointestinal tract (GIT) responses to a high-amylose resistant starch (RS) product were compared to those observed when RS was combined with whole grain (WG) and to controls with low RS intake in rats fed moderate or high fat diets. Regardless of fat intake, rats fed RS or WG + RS diets had higher cecum weights, higher intestinal quantities of short chain fatty acids, and lower intestinal content pH, and their GIT cells had increased gene expression for gluconeogenesis and barrier function compared to controls. Whereas RS resulted in greater GIT content acetate and propionate and lowest pH, the WG + RS diets yielded higher butyrate. Rats fed the RS diet with MF had higher cecum weights than those fed either the RS diet with HF or the WG + RS diet with either MF or HF. Diets containing combinations of RS and other dietary fibers should be considered for RS-mediated GIT benefits. |
| Databáze: | OpenAIRE |
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