Late coronary artery stenosis regression within the gianturco-roubin intracoronary stent
| Autor: | Cass A. Pinkerton, Edward T.A. Fry, James Van Tassel, Thomas F. Peters, James B. Hermiller, Charles M. Orr, Bruce F. Waller |
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| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Intracoronary stent medicine.medical_treatment Lumen (anatomy) Coronary Disease Constriction Pathologic Coronary stenosis Coronary Angiography Lesion Restenosis Recurrence Internal medicine medicine Humans Angioplasty Balloon Coronary medicine.diagnostic_test business.industry Stent Middle Aged medicine.disease Coronary Vessels Angiography Linear Models Cardiology Female Stents Radiology medicine.symptom Cardiology and Cardiovascular Medicine Complication business Follow-Up Studies |
| Zdroj: | The American Journal of Cardiology. 77:247-251 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/s0002-9149(97)89387-3 |
| Popis: | The late angiographic outcome of the Gianturco-Roubin intracoronary stent has not been well defined. To investigate serial changes within the stent, we studied 23 patients (15 men and 8 women, median age 63) who had late angiographic follow-up (>1 year) after undergoing Gianturco-Roubin stenting for angioplasty-associated acute or threatened native coronary artery closure. Coronary angiography before and after stenting, at 6-month follow-up, and at late return was analyzed with quantitative coronary angiography. The median time from stent deployment to late angiographic follow-up was 27 months. As expected, stenting significantly increased the median minimal lumen diameter (MLD) acutely from 1.0 to 2.46 mm. Median percent diameter stenosis decreased from 66% to 18%. Although at 6 months there was a significant loss of the acute gain (median MLD decreased from 2.46 to 1.9 mm), with a corresponding increase in percent stenosis from 18% to 31%, late angiography demonstrated lesion regression, median MLD increasing from 1.9 to 2.15 mm (p = 0.004), and percent stenosis decreasing from 31% to 21% (p = 0.0026). No patient had a significant decline in minimal lesion diameter, and 5 patients had a >50% increase in MID at late follow-up. Linear regression analysis of 6-month MLD and late lumen gain suggested that lesions with the greatest regression were those with the lowest lumen diameters at 6-month angiography. Late angiographic analysis demonstrated significant lesion regression within the Gianturco-Roubin stent, which was sometimes dramatic. In suggesting that coronary arteriography at 6 months may underestimate the late angiographic benefit of intracoronary stenting, these data have important clinical implications, and imply that patients with a stable clinical course and angiographic stent restenosis may often be followed rather than routinely redilated. |
| Databáze: | OpenAIRE |
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