The enantioselective step in the nickel-catalyzed hydrocyanation of 1,3-cyclohexadiene

Autor:	Dieter Vogt, Michèle Janssen, Jos Wilting, Christian Müller
Přispěvatelé:	Physical Chemistry
Jazyk:	angličtina
Rok vydání:	2006
Předmět:	Diene Chemistry Enantioselective synthesis chemistry.chemical_element General Chemistry 1 3-Cyclohexadiene Biochemistry Catalysis Reductive elimination chemistry.chemical_compound Nickel Colloid and Surface Chemistry Hydrocyanation Organic chemistry Enantiomeric excess
Zdroj:	Wilting, J, Janssen, M H M, Muller, C J & Vogt, D 2006, ' The enantioselective step in the nickel-catalyzed hydrocyanation of 1,3-cyclohexadiene ', Journal of the American Chemical Society, vol. 128, no. 35, pp. 11374-5 . https://doi.org/10.1021/ja064378u Journal of the American Chemical Society, 128(35), 11374-11375. American Chemical Society Journal of the American Chemical Society, 128(35), 11374-5. American Chemical Society
ISSN:	0002-7863
DOI:	10.1021/ja064378u
Popis:	On the basis of deuterium labeling experiments and an equal 1,2-/1,4-product distribution, the reductive elimination of the product has been established to be the enantioselective step in the nickel-catalyzed hydrocyanation of 1,3-cyclohexadiene. This could be achieved by successfully exploiting the rather unique features of this reaction: identical product formation for 1,2- and 1,4-addition, cis addition over the diene, and high enantiomeric excess.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edca6a89b032a47abdde7f50bf5e60e9 https://hdl.handle.net/1871/27870 Zobrazit plný text záznamu