Prognostic significance of diastolic blood pressure in patients with heart failure with preserved ejection fraction
| Autor: | Kumiko Yahikozawa, Takuya Maruyama, Ayako Kozuka, Sho Suzuki, Naoto Hashizume, Yusuke Kanzaki, Hirohiko Motoki, Koichiro Kuwahara, Aya Fuchida |
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| Rok vydání: | 2021 |
| Předmět: |
Acute coronary syndrome
medicine.medical_specialty genetic structures Blood Pressure 030204 cardiovascular system & hematology DBP Ventricular Function Left Coronary artery disease 03 medical and health sciences 0302 clinical medicine Diastolic blood pressure Internal medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Aged Heart Failure Ejection fraction business.industry Heart failure readmission Hazard ratio Stroke Volume HFpEF Prognosis medicine.disease Cardiac surgery Blood pressure Heart failure Cardiology Original Article Cardiology and Cardiovascular Medicine Heart failure with preserved ejection fraction business circulatory and respiratory physiology |
| Zdroj: | Heart and Vessels |
| ISSN: | 1615-2573 0910-8327 |
| Popis: | Although systolic blood pressure (SBP) is routinely considered when treating acute heart failure (HF), diastolic blood pressure (DBP) is hardly been assessed in the situation. There are no previous studies regarding the predictive value of DBP in elderly patients with HF with preserved ejection fraction (HFpEF) in Japan. This study aimed to investigate the prognostic significance of DBP in patients with acute decompensated HFpEF. We analyzed data of all HFpEF patients admitted to Shinonoi General Hospital for HF treatment between July 2016 and December 2018. We excluded patients with acute coronary syndrome and severe valvular disease. Patients were divided into two groups according to their median DBP; the low DBP group (DBP ≤ 77 mmHg, n = 106) and the high DBP group (DBP > 77 mmHg, n = 100). The primary outcome was HF readmission. In 206 enrolled patients (median 86 years), during a median follow-up of 302 days, the primary outcome occurred in 48 patients. The incidence of HF readmission was significantly higher in the low DBP group (33.0% vs 18.5%, p = 0.024). In Kaplan–Meier analysis, low DBP predicted HF readmission (Log-rank test, p = 0.013). In Cox proportional hazard analysis, low DBP was an independent predictor of HF readmission after adjustment for age, sex, SBP, hemoglobin, serum albumin, serum creatinine, B-type natriuretic peptide, renin-angiotensin system inhibitors, calcium channel blockers, left ventricular ejection fraction, coronary artery disease, and whether they live alone (hazard ratio, 2.229; 95% confidence interval, 1.021–4.867; p = 0.044). Low DBP predicted HF readmission in patients with HFpEF. |
| Databáze: | OpenAIRE |
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