Fine structure of the intercalated disc and cardiac junctions in the black widow spider Latrodectus mactans
| Autor: | Bon-Jin Ku, Myung-Jin Moon, Yan Sun, Seung-Min Lee |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
02 engineering and technology
Cell junction 03 medical and health sciences medicine Cardiac muscle Spider Latrodectus mactans 030304 developmental biology 0303 health sciences Syncytium Microscopy Sarcolemma biology Intercalated disc Chemistry Cardiac junction Research QH201-278.5 Gap junction General Medicine 021001 nanoscience & nanotechnology biology.organism_classification medicine.anatomical_structure Biophysics cardiovascular system Fascia adherens Fine structure 0210 nano-technology |
| Zdroj: | Applied Microscopy, Vol 50, Iss 1, Pp 1-9 (2020) Applied Microscopy |
| DOI: | 10.21203/rs.3.rs-56121/v1 |
| Popis: | Arthropods have an open circulatory system with a simple tubular heart, so it has been estimated that the contractile pumping structure of the cardiac muscle will be less efficient than that of vertebrates. Nevertheless, certain arthropods are known to have far superior properties and characteristics than vertebrates, so we investigated the fine structural features of intercalated discs and cardiac junctions of cardiac muscle cells in the black widow spider Latrodectus mactans. Characteristically, the spider cardiac muscle has typical striated features and represents a functional syncytium that supports multiple connections to adjacent cells by intercalated discs. Histologically, the boundary lamina of each sarcolemma connects to the basement membrane to form an elastic sheath, and the extracellular matrix allows the cells to be anchored to other tissues. Since the intercalated disc is also part of sarcolemma, it contains gap junctions for depolarization and desmosomes that keep the fibers together during cardiac muscle contraction. Furthermore, fascia adherens and macula adherens (desmosomes) were also identified as cell junctions in both sarcolemma and intercalated discs. To enable the coordinated heartbeat of the cardiac muscle, the muscle fibers have neuronal innervations by multiple axons from the motor ganglion. |
| Databáze: | OpenAIRE |
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