Structure/function relationships within the RNA recognition motif family applied to the hermes gene product
| Autor: | Laurent Thion, Monique Erard |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Models
Molecular Protein Conformation Amino Acid Motifs Molecular Sequence Data RNA-binding protein Biology Crystallography X-Ray Biochemistry Protein Structure Secondary Gene product Structure-Activity Relationship Protein structure Structural Biology Animals Drosophila Proteins Amino Acid Sequence Peptide sequence Genetics RNA recognition motif Sequence Homology Amino Acid fungi RNA RNA-Binding Proteins General Medicine Tripartite motif family Drosophila Sequence motif Protein Binding |
| Zdroj: | Protein and peptide letters. 9(2) |
| ISSN: | 0929-8665 |
| Popis: | The RNA Recognition Motif (RRM) family of RNA-binding domains comprises distinct structural subclasses which can be equated to various types of cognate RNA(s) in relation to biological functions. By identifying structural templates within the appropriate RRM subclass, we have homology-modelled the three-dimensional structure of the hermes gene-encoded RRM. Our findings lead us to propose potential RNA targets for the corresponding protein and to predict possible functions in RNA metabolism during heart development. |
| Databáze: | OpenAIRE |
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