Blood Flow Measurement During Distraction Osteogenesis
| Autor: | Koji Minematsu, Junichi Taki, Katsuro Tomita, Hiroyuki Tsuchiya |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Callus formation medicine.medical_treatment education Osteogenesis Distraction Bone Neoplasms Technetium Tc 99m Medronate Scintigraphy External fixation medicine Humans Orthopedics and Sports Medicine Tibia Child Radionuclide Imaging Aged Leg Chemotherapy medicine.diagnostic_test business.industry Femoral Neoplasms Soft tissue General Medicine Blood flow Middle Aged Surgery Regional Blood Flow Distraction osteogenesis Female Radiopharmaceuticals business |
| Zdroj: | Clinical Orthopaedics and Related Research. 347:229 |
| ISSN: | 0009-921X |
| DOI: | 10.1097/00003086-199802000-00028 |
| Popis: | The regional blood flow of 30 distraction segments in 27 patients was measured during distraction osteogenesis. There were three groups of patients. Group A consisted of seven patients with high grade malignant tumors who received chemotherapy preoperatively and postoperatively. Group B consisted of eight patients with low grade malignant and aggressive benign tumors, who all were treated without chemotherapy. Group C (the control group) consisted of 12 patients with nontumoral conditions. Using quantitative technetium scintigraphy, the regional blood flow within the distracted segment and surrounding soft tissues was measured. The measured radioisotope count was expressed as the ratio of the distracted site to the control site (blood flow ratio). The blood flow ratio for all the cases averaged 1.70 +/- 0.70. Group A had a lower blood flow ratio, which was statistically significant in comparison with the other two groups. The external fixation index showed no significant difference in callus formation among these three groups. No correlation was found between the blood flow ratio and external fixation index. Chemotherapy decreases regional blood flow, but with distraction osteogenesis the regional blood flow can be kept within the normal range or higher. Distraction osteogenesis may overcome the effects of chemotherapy by increasing blood flow. |
| Databáze: | OpenAIRE |
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