Risk factors of the peptic ulcer bleeding in aging uremia patients under regular hemodialysis
| Autor: | Ping-Hsien Chen, Shih-Hao Young, Ming-Chih Hou, Fa-Yauh Lee, Xi-Hsuan Lin, Yuan-Jen Wang, Jiing-Chyuan Luo, Chung-Chi Lin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Cirrhosis medicine.medical_treatment 030232 urology & nephrology Disease 03 medical and health sciences 0302 clinical medicine Adrenal Cortex Hormones Renal Dialysis Risk Factors Internal medicine medicine Humans Aged Proportional Hazards Models Uremia Aged 80 and over lcsh:R5-920 business.industry Anti-Inflammatory Agents Non-Steroidal General Medicine medicine.disease Peptic Ulcer Hemorrhage National health insurance 030211 gastroenterology & hepatology Female Peptic ulcer bleeding Hemodialysis Database research business lcsh:Medicine (General) Kidney disease |
| Zdroj: | Journal of the Chinese Medical Association, Vol 81, Iss 12, Pp 1027-1032 (2018) |
| ISSN: | 1726-4901 |
| Popis: | Background: Previous studies have shown that uremia patients under hemodialysis (HD) have a significantly higher occurrence of peptic ulcer bleeding (PUB) than healthy controls and that elderly patients remain at high risk of peptic ulcer disease (PUD) and PUB. Here we aimed to identify the risk factors for PUB in aging (≥65-years-old) uremic patients under regular HD. Methods: Using data from the National Health Insurance Research Database of Taiwan, we compared 18,252 aging regular HD patients and 17,883 age-, gender-, and medication-matched patients without kidney disease (control group). The log-rank test was performed to analyze the differences in accumulated hazard of PUB between the two groups. Cox proportional hazard regressions were performed to evaluate independent risk factors for PUB between the two groups and identify risk factors of PUB in aging HD patients. Results: In a 7-year follow-up, aging HD patients had significantly higher incidences of PUB than the matched controls (p |
| Databáze: | OpenAIRE |
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