Estimating a worker entry interval for the carbamate pesticide furadan 4F insecticide
Autor: | W. F. Serat |
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Rok vydání: | 1978 |
Předmět: |
Carbamate
Citrus Insecticides Chromatography Gas Time Factors Health Toxicology and Mutagenesis medicine.medical_treatment Toxicology chemistry.chemical_compound Carbofuran medicine Humans Cholinesterase Residue (complex analysis) Chromatography biology Pesticide Residues food and beverages General Medicine Pesticide Plants Pollution Cholinesterase inhibition Agricultural Workers' Diseases chemistry Organic phosphates biology.protein Interval (graph theory) |
Zdroj: | Archives of environmental contamination and toxicology. 7(1) |
ISSN: | 0090-4341 |
Popis: | Existing methods for the calculation of worker entry intervals by the use of kinetic data have focused on the anticholinesteratic organic phosphates. As carbamate pesticides share with these materials a common site for inhibition, the kinetic method was applied in estimating an entry interval for the carbamate, carbofuran, applied to citrus and grapes as Furadan 4F. No allowance was made for the more transient carbamylation of cholinesterase attributed to N-methyl carbamates, compared with the phosphorylation of the enzyme by organic phosphates. Thus, a measure of safety was built into the calculations which can then be used to establish safe reentry intervals to insure residue levels below the physiological threshold for cholinesterase inhibition. |
Databáze: | OpenAIRE |
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