Severe eosinophilic asthma: a roadmap to consensus
| Autor: | Buhl, R, Humbert, M, Bjermer, L, Chanez, P, Heaney, LG, Pavord, I, Quirce, S, Virchow, JC, Holgate, S, Expert Group of the European Consensus Meeting for Severe Eosinophilic Asthma |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Consensus Eosinophilic asthma macromolecular substances Severity of Illness Index Biological Factors 03 medical and health sciences 0302 clinical medicine immune system diseases Eosinophilic medicine Humans 030212 general & internal medicine Pulmonary Eosinophilia Intensive care medicine Societies Medical Task force business.industry Disease Management Asthma respiratory tract diseases Europe 030228 respiratory system Immunology business |
| Zdroj: | European Respiratory Journal. 49:1700634 |
| ISSN: | 1399-3003 0903-1936 |
| DOI: | 10.1183/13993003.00634-2017 |
| Popis: | Asthma is widely accepted as a complex heterogeneous condition with diverse pathophysiological mechanisms, clinical presentations, comorbidities, physiological characteristics, pathology and outcomes that is typically best managed by a multidisciplinary team [1–4]. Severe asthma is recognised as a major unmet need with a high personal and social impact, as well as a high burden on healthcare resources [4]. As a consequence of advances in the development of precision medicines for patients with severe asthma, the need to identify asthma subtypes by phenotype based on clinical, functional or inflammatory parameters is becoming a mandatory part of management [4–6]. Severe eosinophilic asthma (SEA), also referred to as severe asthma with eosinophilia, is yet to be clearly defined and warrants further discussion. A task force has identified key consensus issues for defining, diagnosing and treating severe eosinophilic asthma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|