Preoperative risk factors including serum levels of potassium, sodium, and creatinine for early mortality after open abdominal surgery:a retrospective cohort study
| Autor: | Henrik L. Jørgensen, Damoun Hannani, Sara Liest, Lars N. Jorgensen, Pia Bükmann Larsen, Mohamed Ebrahim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
lcsh:Surgery Preoperative care Cohort Studies 03 medical and health sciences chemistry.chemical_compound Electrolytes 0302 clinical medicine Risk Factors 030202 anesthesiology Internal medicine Abdomen Preoperative Care Clinical endpoint Humans Medicine Mortality Retrospective Studies Creatinine Frailty business.industry Sodium 030208 emergency & critical care medicine Retrospective cohort study General Medicine lcsh:RD1-811 Surgery Algorithm Treatment Outcome medicine.anatomical_structure chemistry Surgical Procedures Operative Cohort Potassium business Research Article Cohort study Abdominal surgery |
| Zdroj: | Ebrahim, M, Larsen, P B, Hannani, D, Liest, S, Jørgensen, L N & Jørgensen, H L 2021, ' Preoperative risk factors including serum levels of potassium, sodium, and creatinine for early mortality after open abdominal surgery : a retrospective cohort study ', BMC Surgery, vol. 21, no. 1, 62 . https://doi.org/10.1186/s12893-021-01070-0 BMC Surgery, Vol 21, Iss 1, Pp 1-9 (2021) BMC Surgery |
| DOI: | 10.1186/s12893-021-01070-0 |
| Popis: | Background In hospitalized patients, abnormal plasma electrolyte concentrations are frequent and have been linked to poor outcomes following acute surgery. The aim of this study was to assess whether preoperative plasma levels of potassium, sodium, and creatinine at the time of admission were associated with 30-day mortality in patients following open abdominal surgery. Methods This was a single-center register-based retrospective study. By means of electronic search in a maintained surgery database, all patients (n = 4177) aged ≥ 60 years old undergoing open surgery in our department from January 2000 to May 2013 were identified. Plasma was assessed within 30 days prior to surgery. The primary endpoint was 30-day postoperative mortality. The association between mortality and plasma levels of potassium, sodium, and creatinine were examined using Cox proportional hazard models. Results A total of 3690 patients were included in the study cohort. The rates of abnormal preoperative plasma levels were 36, 41, and 38% for potassium, sodium, and creatinine, respectively. The overall 30 day mortality was 20%. A predictive algorithm for 30 day mortality following abdominal surgery was constructed by means of logistic regression showing excellent distinction between patients with and without a fatal postoperative outcome. Conclusion Apart from demographic factors (age, sex, and emergency surgery), preoperative imbalance in potassium, sodium and creatinine levels were significant independent predictors of early mortality following open abdominal surgery. |
| Databáze: | OpenAIRE |
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