Nuclear magnetic resonance imaging in multiple sclerosis

Autor: Leon Kaufman, David Norman, Catherine M. Mills, Michael J. Aminoff, Lawrence E. Crooks, Steven A. Lukes, Hillel S. Panitch
Rok vydání: 1983
Předmět:
Zdroj: Annals of Neurology. 13:592-601
ISSN: 1531-8249
0364-5134
DOI: 10.1002/ana.410130603
Popis: Ten patients with definite multiple sclerosis underwent hydrogen nuclear magnetic resonance imaging with a 3.5 kilogauss superconducting magnet, using the inversion recovery and spin-echo techniques of signal acquisition. Results were compared with high-resolution x-ray computed tomography. Spin-echo images demonstrated abnormal regions as areas of variably increased signal intensity. The contrast between abnormal and normal white matter improved as the intervals between sequential radiofrequency pulses and between pulse administration and signal sampling were increased. Inversion recovery images demonstrated abnormal areas as regions of decreased signal intensity but did not visualize lesions as well as spin-echo imaging. Spin-echo and inversion recovery imaging each demonstrated more extensive abnormalities than did computed tomography.
Databáze: OpenAIRE