Research site mentoring: A novel approach to improving study recruitment
Autor: | Danielle Beck, Marcus R. Johnson, Tawni Kenworthy-Heinige, Beata M. Planeta, Margaret Antonelli, Emily B. Broussard, Lynn M. Tommessilli, Karen Bratcher, Aliya Asghar |
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Rok vydání: | 2018 |
Předmět: |
Network of Dedicated Enrollment Sites (NODES)
medicine.medical_specialty 030204 cardiovascular system & hematology Cooperative Studies Program (CSP) Article 03 medical and health sciences 0302 clinical medicine Mentorship Department of Veterans Affairs medicine Clinical research site mentorship 030212 general & internal medicine Pharmacology lcsh:R5-920 business.industry General Medicine 16. Peace & justice 3. Good health Clinical trial Physical therapy Site-based recruitment CONFIRM Study recruitment lcsh:Medicine (General) Monthly average business |
Zdroj: | Contemporary Clinical Trials Communications Contemporary Clinical Trials Communications, Vol 9, Iss C, Pp 172-177 (2018) |
ISSN: | 2451-8654 |
Popis: | Background/Aims The VA Cooperative Studies Program's (CSP) Network of Dedicated Enrollment Sites (NODES) is a consortium of nine VA medical centers (VAMCs) with teams (nodes) dedicated to enhance performance, compliance, and management of CSP multi-site clinical trials. The West Haven CSP Coordinating Center (WH-CSPCC), study coordinating center for CSP #577, Co lo n oscopy Versus F ecal I mmunochemical Test (FIT) in R educing M ortality from Colorectal Cancer (CONFIRM) trial, and NODES piloted a “site mentoring” (hub-and-spoke) model. In this model, a node site would work one-on-one with a low enrolling CONFIRM site to identify and overcome barriers to recruitment. The aim was to determine the impact of a research site mentoring model on study recruitment and examine site-level characteristics that facilitate or impede it. Results Sites in the mentorship pilot had an average improvement of 5 ± 4 participants randomized per month (min −2.6; max 11.6; SD 4.3). Four of ten sites (40%) demonstrated continuous improvement in the average number of randomized participants per month after the pilot intervention and at three-month follow-up (post-intervention), as compared to the five-month period preceding the intervention. An additional two sites (20%) demonstrated improvement in the average number of randomized participants per month after the pilot intervention, and sustained that level of improvement at three-month follow-up (post-intervention). Additionally, six of ten sites (60%) demonstrated an increased number of participants screened for eligibility immediately following the intervention and at three-month follow-up (post-intervention). Only one site showed a decreased monthly average of randomized participants shortly after the intervention and through the three-month follow-up period. Conclusions The site mentoring model was successful in improving recruitment at low enrolling CONFIRM sites. An additional feasibility assessment is needed to determine if this mentoring model will be effective with other CSP trials. |
Databáze: | OpenAIRE |
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