Effects of ZnO/TiO2 nanoparticle and TiO2 nanotube additions to dense polycrystalline hydroxyapatite bioceramic from bovine bones

Autor: Rogério Erbereli, L. A. Pires, Brunna Mota Ferrairo, Carlos Alberto Fortulan, Orisson Ponce Gomes, Ana Flávia Sanches Borges, João Fiore Parreira Lovo, Lucas José de Azevedo Silva, J.A. Griggs, Paulo Noronha Lisboa-Filho, José Henrique Rubo
Přispěvatelé: Universidade de São Paulo (USP), Universidade Estadual Paulista (Unesp), Univ Mississippi
Rok vydání: 2020
Předmět:
Zdroj: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
ISSN: 0109-5641
DOI: 10.1016/j.dental.2019.11.006
Popis: Made available in DSpace on 2020-12-10T19:47:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-02-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Objectives. A bovine dense hydroxyapatite ceramic (HA) was produced as new biomaterial, however, the production of a material with consistently high flexural strength remains challenging. The objective of this study was to evaluate the effects of ZnO nanoparticles, TiO2 nanoparticles, and TiO2 nanotubes (1%, 2%, and 5% by weight) on the microstructure and flexural strength of a bovine dense hydroxyapatite ceramic (HA). Methods. Discs ((sic) =12.5 mm; thickness =1.3 mm) were prepared and subjected to X-ray diffraction (XRD), and observation with a field emission scanning electron microscope (FE-SEM), biaxial flexural strength (BFS) testing, and Vickers hardness (VH) testing. The BFS and VH data were subjected to ANOVA and Tukey post-hoc tests (alpha = 0.05) and Weibull analysis. Results. The XRD showed that the addition of nanomaterials caused the formation of a secondary phase when 5% of the ZnO nanoparticles was used, or when all percentages of the TiO2 nanoparticles/nanotubes were used, and the HA crystallographic planes were maintained. Differences were not observed between the higher BFS values obtained with pure HA and those obtained with the 5% addition of TiO2 nanoparticles. However, the results were different compared with the other groups (alpha = 0.05). The results obtained by Weibull analysis revealed that the 1%, 2%, and 5% addition of TiO2 nanotubes, and the 1% and 2% addition of TiO2 nanoparticles decreased the HA characteristic strength (sigma(0)), while the Weibull modulus (m) increased when 5% of TiO2 nanoparticles, 1% and 2% of ZnO nanoparticles, and 2% of TiO2 nanoparticles were added, but with no statistical difference from the pure HA. The 5% addition of ZnO2 nanoparticles decreased the sigma(0) without changing m. Moreover, the 5% addition of TiO2 nanoparticles resulted in an m closest to that of pure HA. Regarding the VH results, the blend of HA with 1% and 2% addition of TiO2 nanoparticles exhibited the higher values, which were similar between the different addition ratios (p = 0.102). Moreover, the addition of 5% TiO2 nanoparticles resulted in higher value compared with pure HA. Significance. This study demonstrated that the HA blend with 5% of TiO2 nanoparticles has the greatest potential as a bovine HA dense bioceramic reinforcement. (C) 2019 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved. Univ Sao Paulo, Dept Operat Dent Endodont & Dent Mat, Bauru Sch Dent, Alameda Dr Octavio Pinheiro Brisolla 9-75, BR-17012901 Bauru, SP, Brazil Univ Sao Paulo, Bauru Sch Dent, Dept Prosthodont & Periodont, Alameda Dr Octavio Pinheiro Brisolla 9-75, BR-17012901 Bauru, SP, Brazil Univ Sao Paulo, Sao Carlos Sch Engn, Dept Mech Engn, Ave Trabalhador Sao Carlense 400, BR-13566590 Sao Carlos, SP, Brazil Sao Paulo State Univ, Sch Sci, Dept Phys, Av Engn Luiz Edmundo Carrijo Coube S-N, BR-17033360 Bauru, SP, Brazil Univ Mississippi, Sch Dent, Dept Biomed Mat Sci, Med Ctr, 2500 North State St,Room D528, Jackson, MS 39216 USA Sao Paulo State Univ, Sch Sci, Dept Phys, Av Engn Luiz Edmundo Carrijo Coube S-N, BR-17033360 Bauru, SP, Brazil FAPESP: 2018/23639-0 FAPESP: 2013/07296-2 CNPq: 154705/2015-2
Databáze: OpenAIRE
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