Choroidal thickness in patients with diabetic retinopathy
| Autor: | Sezin Ozdogan Erkul, Nurhan Dinçer, Hulya Gungel, Sibel Zırtıloğlu, Erkan Unsal, Kadir Eltutar |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
choroidal thickness
medicine.medical_specialty Retina Retinal pigment epithelium optical coherence tomography endocrine system diseases genetic structures business.industry Clinical Ophthalmology Diabetic retinopathy medicine.disease eye diseases Sclera Ophthalmology diabetic retinopathy medicine.anatomical_structure Hemoglobin A Diabetes mellitus medicine Choroid sense organs business Macular edema Original Research |
| Zdroj: | Clinical Ophthalmology (Auckland, N.Z.) |
| ISSN: | 1177-5483 1177-5467 |
| Popis: | Erkan Ünsal, Kadir Eltutar, Sibel ZirtiloÄlu, Nurhan Dinçer, Sezin ÖzdoÄan Erkul, Hülya GüngelDepartment of Ophthalmology, Istanbul Education and Research Hospital, Istanbul, TurkeyPurpose: The aim of the study reported here was to assess choroidal thickness (CT) and central macular thickness (CMT) in patients with diabetic retinopathy.Materials and methods: A total of 151 eyes from 80 patients from the retina department of Istanbul Training and Research Hospital who had type 2 diabetes mellitus with diabetic retinopathy were studied retrospectively in this cross-sectional research. Patients were divided into three groups: mild–moderate nonproliferative diabetic retinopathy without macular edema (NPDR), mild–moderate nonproliferative diabetic retinopathy with macular edema (DME), and proliferative diabetic retinopathy (PDR). In addition, 40 eyes of 20 healthy individuals comprised a control group. Choroidal thickness was measured from the posterior edge of the retinal pigment epithelium to the choroid/sclera junction at 500-µm intervals up to 1,500 µm temporal and nasal to the fovea. The CMT measurement was obtained for each eye. Serum hemoglobin A1c (HbA1c) levels were measured.Results: The study included 191 eyes, comprising 151 eyes of 80 patients and 40 eyes of 20 healthy individuals. Of the 151 patient eyes, 61 had NPDR, 62 had PDR, and 28 eyes had DME. There was no statistically significant difference in age between the groups (P>0.05). In both the PDR and DME groups, the CT was statistically significantly decreased compared with the control group (P |
| Databáze: | OpenAIRE |
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