Immunization Status against Measles, Mumps, Rubella and Varicella in a Large Population of Internationally Adopted Children Referred to Meyer Children’s University Hospital from 2009 to 2018
| Autor: | Elena Chiappini, Paolo Bonanni, Luisa Galli, Cecilia Maria Alimenti, Sara Boccalini, Angela Bechini |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty Immunology lcsh:Medicine Rubella Measles Article Serology varicella Interquartile range immunological status Drug Discovery medicine measles Seroprevalence Pharmacology (medical) Pharmacology seroprevalence business.industry rubella lcsh:R internationally adopted children vaccination medicine.disease Vaccination Infectious Diseases Immunization Vaccine-preventable diseases mumps business |
| Zdroj: | Vaccines, Vol 8, Iss 1, p 51 (2020) Vaccines Volume 8 Issue 1 |
| ISSN: | 2076-393X |
| DOI: | 10.3390/vaccines8010051 |
| Popis: | Control of vaccine preventable diseases (VPDs) is a challenge for healthcare systems. Different studies highlighted the suboptimal immunization of internationally adopted children (IAC). To evaluate the immunization status against measles, mumps, rubella (MMR), and varicella (V) in a large cohort of IAC, data at first screening visit of all IAC (< 18 years) consecutively referred to Meyer Children&rsquo s University Hospital (Florence, Italy) from 2009 to 2018 were collected and analyzed. In total, 1927 children (median age: 5.99 years, interquartile range: 3.33&ndash 8.21) were enrolled. More than half of IAC were unprotected against MMR-V. The reliability of the vaccination documentation of the country of origin was poor, since more than a quarter of the IAC serologically tested were not protected against MMR-V, despite the vaccination documentation attesting previous vaccination. This was significantly more pronounced in children aged 15&ndash 18 years and in those originating from Africa. High rate of discordant serological results/documentation brings up questions regarding the optimal management of IACs, and suggests a rapid, careful, and complete assessment of immunization status timely after IAC&rsquo s arrival. Serological testing of IAC of all ages followed by vaccination of seronegative children should be provided. |
| Databáze: | OpenAIRE |
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