Effect of the route of foot-and-mouth disease virus inftection of piglets on the course of disease
| Autor: | Li D, Bai Xw, Sun P, Chen Yl, Fu Yf, Xie Bx, Cao Wj, Liu Zx, Lu Zj |
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| Rok vydání: | 2010 |
| Předmět: |
Injections
Intradermal Swine viruses animal diseases Injections Intramuscular Virus Random Allocation Virology Animals Potency Medicine Intradermal injection Administration Intranasal Swine Diseases Virulence Foot-and-mouth disease biology business.industry Viral Vaccines General Medicine medicine.disease biology.organism_classification Infectious Diseases Foot-and-Mouth Disease Virus Foot-and-Mouth Disease Immunology Nasal administration Foot-and-mouth disease virus business Intramuscular injection Foot (unit) |
| Zdroj: | Acta Virologica. :311-313 |
| ISSN: | 1336-2305 |
| Popis: | Three different routes of Foot-and-mouth disease virus (FMDV) infection of piglets, namely intranasal (i.n.) through drops, intradermal (i.d.) into the foot, and intramuscular (i.m.) were compared regarding the onset and severity of the disease. The results showed that the i.d. injection of the virus resulted in the fastest onset of the disease. The i.m. injection led to a delayed onset, but the final effect was identical with i.d. injection. Moreover, the i.m. injection was simpler to perform and easier to evaluate. Therefore, the i.m. injection of piglets is recommended as the optimal infection route for evaluation of the FMDV vaccine potency. |
| Databáze: | OpenAIRE |
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