Increase in fast hemoglobin concentration after incubation with acetaldehyde detected by an electrophoretic method
| Autor: | I. Fleming, G. C. Hawthorne, T. C. M. Moms, J. R. Hayes |
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| Rok vydání: | 1984 |
| Předmět: |
Electrophoresis
Agar Gel Chromatography Time Factors Chemical Phenomena Acetaldehyde Medicine (miscellaneous) Half-life In Vitro Techniques Toxicology Psychiatry and Mental health chemistry.chemical_compound Electrophoresis Alcoholism Chemistry Hemoglobins chemistry Biochemistry Yield (chemistry) Humans Hemoglobin Incubation Half-Life |
| Zdroj: | Alcoholism, clinical and experimental research. 8(6) |
| ISSN: | 0145-6008 |
| Popis: | Incubation of acetaldehyde with hemoglobin has been shown by chromatographic methods to result in an increase in fast hemoglobin. We have studied this increase in fast hemoglobin concentration by a gel electrophoretic method. Increases in fast hemoglobin concentration are detected following incubation with concentrations of 100 microM acetaldehyde and no further increase in yield occurs with concentrations greater than 7 mM acetaldehyde. The reaction is complete within 5 hr and the product is stable with a half-life of greater than 12 days. |
| Databáze: | OpenAIRE |
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