Serum levels of carbonylated and nitrosylated proteins in mobbing victims with workplace adjustment disorders
| Autor: | Salvatore Saitta, Simona Abbate, S. Imbesi, E. Abenavoli, Concettina Fenga, Francesco Cimino, Mariateresa Cristani, Paola Lucia Minciullo, Antonella Saija, A. E. Di Rosa, Antonio Speciale, Sebastiano Gangemi, Giovanna Spatari |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Adjustment disorders Nitrosylated proteins medicine.disease_cause Affect (psychology) Statistics Nonparametric Protein Carbonylation Adjustment Disorders medicine Humans Social Behavior Workplace Psychological abuse Psychiatry General Neuroscience Healthy subjects Proteins Mobbing Middle Aged medicine.disease Neuropsychology and Physiological Psychology Oxidative stress Anxiety Female medicine.symptom Protein carbonyl Psychology Protein carbonyl groups Biomarkers Stress Psychological Clinical psychology Workplace adjustment disorders |
| Popis: | Aim: Today the most important problem in the work place is psychological abuse, which may affect the health because of high levels of stress and anxiety. There is evidence that most psychiatric disorders are associated with increased oxidative stress but nothing is reported about the presence of oxidative stress in mobbing victims. Methods: This study has been carried out in a group of 19 patients affected by workplace mobbing-due adjustment disorders, in comparison with 38 healthy subjects, to evaluate whether oxidative stress may be induced by mobbing. Results: Serum levels of protein carbonyl groups and of nitrosylated proteins, biological markers of oxidative stress conditions, were higher than those measured in healthy subjects. Conclusions: These findings may contribute to a better understanding of the redox homeostasis dysregulation occurring in victims of workplace mobbing. |
| Databáze: | OpenAIRE |
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